Is there a way to optimize?

I posted the following email to another Win2k Server Networking newsgroup
last week but got no response. Perhaps someone monitoring this one can
answer my question. If you have a remote office across a very slow WAN link,
is there a way to tweak a Win2k server to send SMB traffic optimized with
those users in mind? Will this improve their effective performance?
Sometimes Outlook, for instance, takes 5 minutes to open up their mailboxes.
Here's the original post, in case you want more info on the scenario.
Jon
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Good morning,
I have a central office and two remote offices connected via Frame Relay.
The port speed at the central office is 512k and at the remotes, 256k. The
CIR is 32k at the remotes with bursting to 384k. Our remote offices do not
seem to get anywhere near the burst speed and queries to the Exchange and SQL
servers at the central office often timeout. Effective bandwith appears to
hover near the CIR with occational bursts to 120k. It has been suggested
that I reconfigure the Win2k servers to run SMB in raw versus block mode.
All I've been able to uncover in the KB are references to WindowsNT regarding
this issue.
Any pointers to KB articles describing how to configure Windows 2000 servers
for optimal WAN traffic communication would be greatly appreciated.
The carrier, ATT, analyzed sniffer traces and determined that the PVCs
appear configured correctly.
If you look at this scenario and have another idea of what might be going
on, I'd certainly like to hear what you have to say.
Thanks in advance for any ideas!
Jon : )