If you have a broadband router with firewall, you have some safety. But I'd
still run something like ZoneAlarm (free download) on each PC. Set
ZoneAlarm to deny all access to the network and then selectively enable
applications as you see fit.
You also need at least a copy of A/V that will check networked drives. You
can then network all the drives to the one PC and have it check them. But
beware that this could be slow over the network - you'll just have to try it
and see whether this works. Be sure to run a full scan every night to catch
anything that gets through.
Also, if you go this A/V route, I'd run a small batch job periodically that
checks the network drives, restores them if they fail (try running a quick
dir) and if all else fails, beeps madly until you sort out the problem.
Schedule this task ever hour or so to ensure that the network shares stay
up.
Finally, have you come across AdAware and its ilk? My father's machine was
infested with spyware which was not detected as a virus but which caused all
manner of hell. Running AdAware (again, there is a free download
www.lavasoft.com) periodically will keep such nasties at bay.
Be afraid, be very afraid and you can't go wrong. Drop your guard and you
will ;-).
Paul DS.