It appears you're using subnetting, which is a software way of networking, layer 2 (mac addressing and ARP broadcasts) should still work fine, provided that this is the case... read on
SUGGESTION: 2 static RIP entries upon each gateway inbetween? provided there isnt too much filtering on the cisco or the gateways/routers between...
SUBNET 1 to SUBNET 2
destination : 222.222.222.222.0 ---- 0 = whole network
MASK: 255.255.255.224
Gateway: 222.222.222.1
SUBNET 2 to SUBNET 1
destination : 111.111.111.111.0 ---- 0 = whole network
MASK: 255.255.255.192
Gateway: 111.111.111.1
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